Estimating GFR and GFR decline in patients with T2DM
نویسندگان
چکیده
منابع مشابه
Angiotensin II-mediated GFR decline in subtotal nephrectomy is due to acid retention associated with reduced GFR.
BACKGROUND Angiotensin II (AII) mediates glomerular filtration rate (GFR) decline in animals with subtotal nephrectomy (Nx), but the mechanisms for increased AII activity are unknown. Because reduced GFR of Nx is associated with acid (H(+)) retention that increases kidney AII, AII-mediated GFR decline might be induced by H(+) retention. METHODS We measured GFR and kidney microdialyzate H(+) a...
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ژورنال
عنوان ژورنال: Nature Reviews Nephrology
سال: 2013
ISSN: 1759-5061,1759-507X
DOI: 10.1038/nrneph.2013.50